منابع مشابه
Electrochemotherapy of tumours
Electrochemotherapy is a combined use of certain chemotherapeutic drugs and electric pulses applied to the treated tumour nodule. Local application of electric pulses to the tumour increases drug delivery into cells, specifically at the site of electric pulse application. Drug uptake by delivery of electric pulses is increased for only those chemotherapeutic drugs whose transport through the pl...
متن کاملElectrochemotherapy in treatment of tumours.
AIM Electrochemotherapy is a local drug delivery approach aimed at treatment with palliative intent of cutaneous and subcutaneous tumour nodules of different histologies. Electrochemotherapy, via cell membrane permeabilising electric pulses, potentiates the cytotoxicity of non-permeant or poorly permeant anticancer drugs with high intrinsic cytotoxicity, such as bleomycin or cisplatin, at the s...
متن کاملElectrochemotherapy in treatment of tumours
Electrochemotherapy is a combination therapy for cancer and consists of electroporation and treatment using cytostatic agents. Electroporation is a method that through an electric field temporarily opens the cell membrane which enhances the cytotoxic effect. Electrochemotherapy is used to a limited extent in Sweden and an essential question is if there is evidence that the method is effective a...
متن کاملElectrochemotherapy
Electrochemotherapy is now in development for treatment of deep-seated tumors, like in bones and internal organs, such as liver. The technology is available with a newly developed electric pulse generator and long needle electrodes; however the procedures for the treatment are not standardized yet. In order to describe the treatment procedure, including treatment planning, within the ongoing cl...
متن کاملCalculation of the electrical parameters in electrochemotherapy of solid tumours in mice.
Electrochemotherapy is a novel approach in chemotherapeutic drug delivery into tumours. Short intense direct current electric pulses are applied to tumour tissue causing electropermeabilisation thus enabling entrance of chemotherapeutic drugs into cells which otherwise do not easily penetrate. A three dimensional anatomically based finite element model of the mouse with injected subcutaneous so...
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ژورنال
عنوان ژورنال: Current Oncology
سال: 2009
ISSN: 1718-7729
DOI: 10.3747/co.v16i2.368